Asymmetric Epoxidation Of Dihydronaphthalene With A Synthesized Jacobs :: essays research papers

Asymmetric Epoxidation of Dihydronaphthalene with a Synthesized Jacobsen's Catalyst Abstract. 1,2 diaminocyclohexane was reacted with L-(+)-tartaric acid to yield (R,R)-1,2-diaminocyclohexane mono-(+)-tartrate salt. The tartrate salt was then reacted with potassium carbonate and 3,5-di-tert-butylsalicylaldehyde to yield (R,R)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine, which was then reacted with Mn(OAc)2*4H2O and LiCl to form Jacobsen's catalyst. The synthesized Jacobsen's catalyst was used to catalyze the epoxidation of dihydronaphthalene. The products of this reaction were isolated, and it was found that the product yielded 1,2-epoxydihydronaphthalene as well as naphthalene. Introduction   Ã‚  Ã‚  Ã‚  Ã‚  In 1990, professor E.N. Jacobsen reported that chiral manganese complexes had the ability to catalyze the asymmetric epoxidation of unfunctionalized alkenes, providing enantiomeric excesses that regularly reaching 90% and sometimes exceeding 98% . The chiral manganese complex Jacobsen utilized was [(R,R)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2- cyclohexanediaminato-(2-)]-manganese (III) chloride (Jacobsen's Catalyst). (R,R) Jacobsen's Catalyst Jacobsen's catalyst opens up short pathways to enantiomerically pure pharmacological and industrial products via the synthetically versatile epoxy function .   Ã‚  Ã‚  Ã‚  Ã‚  In this paper, a synthesis of Jacobsen's catalyst is performed (Scheme 1). The synthesized catalyst is then reacted with an unfunctional alkene (dihydronaphthalene) to form an epoxide that is highly enantiomerically enriched, as well as an oxidized byproduct.   Ã‚  Ã‚  Ã‚  Ã‚  Jacobsen's work is important because it presents both a reagent and a method to selectively guide an enantiomeric catalytic reaction of industrial and pharmacological importance. Very few reagents, let alone methods, are known to be able to perform such a function, which indicates the truly groundbreaking importance of Jacobsen's work. Experimental Section   Ã‚  Ã‚  Ã‚  Ã‚  General Protocol. 99% L-(+)- Tartaric Acid, ethanol, dihydronaphthalene and glacial acetic acid were obtained from the Aldrich Chemical Company. 1,2 diaminocyclohexane (98% mix of cis/trans isomers) and heptane were obtained from the Acros Chemical Company. Dichloromethane and potassium carbonate were obtained from the EM Science division of EM Industries, Inc. Manganese acetate was obtained from the Matheson, Coleman and Bell Manufacturing Chemists. Lithium chloride was obtained form the JT Baker Chemical Co. Refluxes were carried out using a 100 V heating mantle (Glas-Col Apparatus Co. 100 mL, 90 V) and 130 V Variac (General Radio Company). Vacuum filtrations were performed using a Cole Parmer Instrument Co. Model 7049-00 aspirator pump with a Bà ¼chner funnel. For Thin Layer Chromatography (TLC) analysis, precoated Kodak chromatogram sheets (silica gel 13181 with fluorescent indicator) were used in an ethyl acetate/hexane (1:4) eluent. TLC's were visualized using a UVP Inc. Model UVG-11 Mineralight Lamp (Short-wave UV-254 nm, 15 V, 60 Hz, 0.16 A). Masses were taken on a Mettler AE 100. Rotary evaporations were performed on a Bà ¼chi Rotovapor-R. Melting points were determined using a Mel-Temp (Laboratory Devices, USA) equipped with a Fluke 51 digital thermometer (John Fluke Manufacturing Company, Inc.). Optical rotations ([a]D) were measured on a Dr. Steeg and Renter 6mbH, Engel/VTG 10 polarimeter.

Summary Response Essay Instruct

In the article, Blinder cites reliable evidence to successfully argue his opinion that the American education system needs to be revised in order to better prepare workers for employment in the current market. In the first section of the Blinder article, he starts off talking about much education one should accomplish. Blinder states, â€Å"In a progressive society, such as worrisome social phenomenon might elicit some strong policy responses, such as more compensatory education, stepped-up efforts at retraining, reinforcement of the social safety net† (Blinder 9).Americans are shredding the safety net; they keep on taking away reinforcements that help pep the playing field â€Å"fair. † According to Blinder, an effect of this is Social Darwinism, where the work force has become survival of the fittest. Employers are looking for people with a high level of education and good people skills. Having good people means being able to communicate well with others; it is a soft skill you must acquire. Later on in the article, Blinder talks about offspring. In the article he explains that offspring is, â€Å"the movement of jobs overseas† (Blinder 9).Countries with lower wages are taking jobs from Americans. Blinder talks about three reasons why jobs are becoming offshore. The first reason is because of â€Å"simple arithmetic. † The second reason is because of the growth in technology; people are now able to do jobs across seas in an efficient manner. This has a negative effect on American workers, because that means fewer job opportunities. Lastly, the number of workers overseas is growing rapidly, and these workers are willing to work longer hours, for lower pay, with few, if any, benefits. Blinder then goes on to talk about different types of jobs.Next in the article, Blinder discusses the different between personal and impersonal jobs. The higher paying jobs are the personal services that roved a specific service that cannot be provided remotely, like a plumber or a hair stylist, for example. He goes on to talk about how the American system of education is not preparing children the right way in school. Schools have them so focused on studying and memorizing for standardized testing instead of personal people skills. Blinder says how, â€Å"starting in elementary schools, we need to develop our youngsters' imaginations and people skills† (Blinder 12).In the end he talks about education needs to better prepare children for the kinds of personal service jobs that cannot be exported. Blinder did a good job explaining his points about the workforce and about how it is changing. With every problem he presented, he argued and discussed a plan to improve that problem. For example, in relation to the personal service jobs, he wants to start children off earlier with learning people skills. Throughout the article, Blinder did not use any confusing words or ideas; he was straightforward and explained himself. He did e xpress his opinions, but they did not come off too strong or heavy-handed.His opinions are supported with evidence and his article is written professionally, leaving he reader clear about what he was trying to say. I agree with what Blinder is talking about in the article. We need to push kids to get a college degree, not for the quantity of education, but for the quality. In America, we push kids to memorize and pass standardized tests that do not help them prepare for the future. Kids need to be learning how to apply what they learned in the real world and how to use that information to interact with people. The truth is, personal jobs are higher in salary. For example, think about doctors.Many medical specialists are foreign; many alienated individuals come to the United States to take advantage of our excellent programs in higher education and stay in the U. S. For work. While I have no problem with this, I also worry that our early education system is failing students since few er and fewer are achieving the kind of advanced education required to be a medical specialist or something similar. Have never lost a job to someone overseas, but my best friend had to move because her dad's job was offshore and they had to relocate for him to look for work. I want to be a special education teacher, which is a personal service, for now.It scares me with all this growth in technology. Look how many online schools there are now. Will one day in the future there be no teachers, just assignments on a computer screen? We need to learn from the past and use it to prepare for the future in order to be successful in the workplace. What if your job is exported? In the article, â€Å"Will Your Job Be Exported,† by Alan S. Blinder, he discusses how job exportation has become an unfortunate reality for so many Americans. Many people are losing jobs to people from other countries. Americans have to fight to keep personal service jobs versus impersonal services.

The War For Equality During The 20th Century - 1218 Words

The War for Equality The first half of the Twentieth century witnessed both WWI and WWII and another war as well; the War for Equality. With a racism and persecution at a high level, racial minorities were ready to fight back. In the first half of the Twentieth century the mistreatment of racial minorities led to a War for Equality; fought on many levels with varying levels of success. The war was fierce and did not end in the first half of the Twentieth Century. Like any war the War for Equality had its’ causes, in this case the war was brought about by the continued mistreatment of racial minorities. This mistreatment came in many forms: segregation, violation of other civil rights, and violence. Racial minorities faced segregation on different levels. Blacks were kept out of public facilities in the South, Mexicans in the West, and Chinese out of America itself. In 1896 The Supreme Court case, Plessy v. Ferguson, determined separate public facilities were constitutional as long they were equal, allowing segregation of racial minorities. Segregated facilities rarely proved equal. While the Supreme Court ruling kept blacks out of white facilities, the Chinese Exclusion Act kept the Chinese out of America. The Chinese Exclusion Act, renewed in 1902, made it increasingly difficult for Chinese to enter America, while also making it easier for them to be deported (Chinese Exclusion Act). Consequently, Mexicans filled the role of cheap la borers that Chinese previouslyShow MoreRelatedJohn Locke on Liberty and Equality933 Words   |  4 PagesLiberalism is a political philosophy based on the ideas of liberty and equality; it supports the ideas of civil rights, freedom of religion, freedom of press, and free trade. Liberalism traces its origins to the works of John Locke in the seventeenth century and the philosophy of enlightenment in the eighteenth century. Locke wrote that every man has a natural right to life, liberty and property (â€Å"All mankind being all equal and independent, no one ought to harm another in his life, health, libertyRead MoreRationality in Humans Essay793 Words   |  4 Pagesthose who do not believe. If there is a war, there will be those that want peace. If there is a political movement, there will be those that disagree. Humans are bound to go against their own believes, their own strategies, and their own establishments. Nothing is forever. History portrays people going against the acce pted ideologies. It shows the everlasting change of the society. First, they thought that God was the explanation to everything. A century later, they started doubting the Bible. TheRead MoreThe Evolution of Gender Roles and its Role in Society1505 Words   |  7 Pagesinfluenced society. The slow progress of woman’s rights throughout humanities led to an explosion of woman’s rights throughout the 20th century and that trend will only continue on into the rest of the 21st century. First, it is important to understand how gender roles first differentiated amongst males and females in prehistoric cultures and the civilizations thereafter. During the Paleolithic period (ca. 6 million to 10,000 B.C.E) the earliest of humankind lived a nomadic way of life (Fiero). Men wereRead MoreWomen‚Äà ´s Suffrage Movement of Europe1187 Words   |  5 PagesThroughout history, women have struggled for equality in all parts of the world. European women fought for suffrage for an extremely long period of time before they were granted full voting rights. Each country approved women’s suffrage at different times, but it occurred in most European countries in the early 20th century. The first country to develop universal suffrage was Finland in the year 1906(â€Å"Women’s Suffrage in Europe†). One of the last countries to become open about women’s voting rightsRead MoreI Have A Dream Speech By Reverend Martin Luther King Jr.926 Words   |  4 PagesThe Equality of Some A little over 50 years ago, Reverend Martin Luther King Jr. delivered his â€Å"I have a Dream Speech† in front of thousands addressing the racism in America. Though racism was a big issue in the United States during the 20th century, and may still be in a few areas today, he was not only addressing the problem of it, but the equality of men. In his speech he quoted words directly from the Declaration of Independence stating, â€Å"I have a dream that one day this nation will rise upRead MoreSoviet Revolutions And The Soviet Revolution1194 Words   |  5 PagesThe 20th century was a tumultuous time all around the world. The 1900s saw two world wars and several revolutions. Among these revolutions, Russia and China stand out among them all. These two countries were the first two to fall to communist revolutions. Communists focused on eliminating class systems and creating a society where property is publicly owned and everyone is paid according to their abilities. Communists believed that this type of society would be better for all people. This ideal societyRead MoreEssay On How Have We Fail1123 Words   |  5 PagesHow Have We Failed America has been failing to live up to the expectations of its founding fathers since the very beginning. Our founding fathers had envisioned a country that would ensure equality, justice, and liberty for all while carrying out general welfare and ensuring domestic tranquility. It should have been our first and foremost duty to make that vision a reality since these values are the very foundation of America. But throughout history, America has suffered from racism, injustice, exploitationRead MoreThe During The Mid 20th Century1657 Words   |  7 Pagesthe spate of transformation that started during the mid 20th century is: how can the history of the mid 1900s be construed in one, single, wholly encompassing idea? The past 70 years since the end of World War II have seen momentous changes to numerous countries all around the world. Each country have experienced developments, both negative and positive, to the social, political, and economic state of themselves. The history of the la ter twentieth century can be defined with the idea of reformationRead MoreWomen s Rights Movement And The Demand For Women Suffrage1650 Words   |  7 Pages19th century from a variety of other movements. A major goal of the woman s rights movement was to change public opinion regarding women s capacities and rights. Suffrage was one of several reforms intended to end the significant legal, political, religious, and cultural discriminations against nineteenth century women. Suffrage became the primary goal of the woman s rights movement during the 1850s and remained so until women finally achieved the right to vote in 1920.During 20th century theyRead MoreThe Tyranny Of White Majority Essay1511 Words   |  7 Pagesfreedom, has been struggling with lingering racism and discrimination throughout the 19th and 20th century. Democratic reform throughout the century were implanted to eliminate the â€Å"tyranny of the white majority† Yet many scholars like Tocqueville, Fredrick Harris and WEB DuBois have challenged these results. The reality is that the tyranny of white majority has continued throughout the 18th to the 21st century resulting in a society that has suppressed and constantly failed to integrate African American